265 South Orange provides a new home for New Haven’s emerging biotech industry

New Haven, CT, USA

Framing the entrance of New Haven’s Square 10 development, 265 South Orange will emerge as a premiere commercial life science laboratory and office space for New Haven. This 270,000 square-foot cutting edge facility is dedicated to advancing life sciences and pharmaceutical research, providing up to 60% spec-lab space, and 40% office space, along with terraces on each floor, a rooftop garden, bike storage, retail, conferencing, and fitness amenities. 

As part of the new Square 10 development, the state-of-the-art life science building is sited between two luxury apartment communities, all centered around a vibrant public plaza & laneway.

A new gateway fostering critical bioscience growth for Connecticut 

 265 South Orange rises from the parking lot that replaced the New Haven Coliseum, a former regional center for sports and entertainment. As part of the Square 10 revitalization, a mixed-use development featuring new residences, office and retail offerings, 265 South Orange will lead the revitalization of a major gateway into the city coming from the south.

Connecting the City of New Haven and Yale University, this project will further diversify the local economy and weave downtown, residential neighborhoods, and Yale University’s medical campus together.  The building presents new opportunities for growing research enterprises stemming from Yale University to remain in Connecticut, fostering significant growth, supporting the local economy and cementing New Haven’s reputation as a regional hub for bioscience and biotechnology research and innovation. 

A 2,400 SF tenant amenity rooftop terrace offers stunning city views toward Long Island Sound.
“265 South Orange will bring a transformative life science development that demonstrates our commitment to creating humane working and community spaces and the responsible use of resources. Ancora’s vision brings New Haven’s first commercial life science building of architectural merit to our city. It is our privilege to be their architects."
— Fred Clarke, FAIA, JIA, RIBA

Flexible design supports evolving research needs 

The design features spaces for focused lab bench work, fully equipped to meet current wet lab requirements, comfortable conference and meeting places that foster cooperation and collaboration, office environs enhanced with natural lighting and calm, quiet spaces conducive to thought that precedes innovation. The building is pre-certified LEED Gold and is expected for completion in 2026.  

265 South Orange creates a new gateway into the heart of downtown New Haven and the city's burgeoning life science research industry.

More About the Project

Project Team

Principal Collaborators

  • Associate Architect: Jacobs
  • Structural Engineer: McNamara Salvia
  • MEP Engineer: BR+A Consulting Engineers

Project Information

  • Location: New Haven, CT
  • Client: Ancora L&G
  • Size: 267,000 sq. ft / 24,805 sq. m.
  • Completion: 2026
  • Firm Role: Full Service Architect
  • Rendering Credit: DeVisual